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Determination of optical scattering properties of highly-scattering media in optical coherence tomography images

机译:光学相干断层扫描图像中高散射介质光学散射特性的测定

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摘要

We developed a new algorithm that fits optical coherence tomography (OCT) signals as a function of depth to a general theoretical OCT model which takes into account multiple scattering effects. With use of this algorithm, it was possible to extract both the scattering coefficient and anisotropy factor from a particular region of interest in an OCT image. The extraction algorithm was evaluated against measurements from an integrating sphere on a set of tissue phantoms and yielded valid results. Finally, a preliminary ex vivo OCT investigation on human aortic specimen indicated that the algorithm may contribute importantly to differentiation between normal and atherosclerotic arteries. We conclude that this algorithm may facilitate tissue characterization by OCT.
机译:我们开发了一种新算法,该算法将光学相干断层扫描(OCT)信号作为深度的函数,适用于考虑了多重散射效应的一般理论OCT模型。使用此算法,可以从OCT图像的特定感兴趣区域中提取散射系数和各向异性因子。针对来自一组组织体模上积分球的测量结果评估了提取算法,并得出了有效的结果。最后,对人的主动脉标本进行的体外离体OCT初步研究表明,该算法可能对区分正常动脉和动脉粥样硬化动脉起重要作用。我们得出的结论是,该算法可能有助于通过OCT进行组织表征。

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